Tail Muscles Become Slow but Fatigable in Chronic Sacral Spinal Rats With Spasticity

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Tail muscles become slow but fatigable in chronic sacral spinal rats with spasticity.

Paralyzed skeletal muscle sometimes becomes faster and more fatigable after spinal cord injury (SCI) because of reduced activity. However, in some cases, pronounced muscle activity in the form of spasticity (hyperreflexia and hypertonus) occurs after long-term SCI. We hypothesized that this spastic activity may be associated with a reversal back to a slower, less fatigable muscle. In adult rats...

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Evidence for plateau potentials in tail motoneurons of awake chronic spinal rats with spasticity.

Motor units of segmental tail muscles were recorded in awake rats following acute (1-2 days) and chronic (>30 days) sacral spinal cord transection to determine whether plateau potentials contributed to sustained motor-unit discharges after injury. This study was motivated by a companion in vitro study that indicated that after chronic spinal cord injury, the tail motoneurons of the sacrocaudal ...

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Spastic tail muscles recover from myofiber atrophy and myosin heavy chain transformations in chronic spinal rats.

Without intervention after spinal cord injury (SCI), paralyzed skeletal muscles undergo myofiber atrophy and slow-to-fast myofiber type transformations. We hypothesized that chronic spasticity-associated neuromuscular activity after SCI would promote recovery from such deleterious changes. We examined segmental tail muscles of chronic spinal rats with long-standing tail spasticity (7 mo after s...

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Ultrasound Evaluation of Spinal Cord in Newborns with Sacral Pit

Background: Sacral pit is a shallow or deep dimple in the lower sacral region, with a reported prevalence of 3-5% among newborns. The aim of the present study was to investigate spinal cord abnormalities in newborns with sacral pit via ultrasound examinations. Methods: In this descriptive study, 3071 infants born at 34-42 weeks of gestation were studied in hospitals affiliated to Islamic Azad U...

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Following chronic sacral spinal cord transection in rats the affected tail muscles exhibit marked spasticity, with characteristic long-lasting tail spasms evoked by mild stimulation. The purpose of the present paper was to characterize the long-lasting reflex seen in tail muscles in response to electrical stimulation of the tail nerves in the awake spastic rat, including its development with ti...

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ژورنال

عنوان ژورنال: Journal of Neurophysiology

سال: 2006

ISSN: 0022-3077,1522-1598

DOI: 10.1152/jn.00456.2005